5 Best CBD Oils for Multiple Sclerosis [2018 Update]

Oils that may relieve the pain...
MarijuanaBreak Staff / Updated on September 29, 2018

cbd oil for multiple sclerosis

Even though Multiple Sclerosis is a complex disorder that researchers have not been able to pinpoint an exact cause for, plenty of consideration has been given to the effects of cannabis – and specifically CBD – for the condition’s varying symptoms.

| “Does CBD work for multiple sclerosis? Early research has shown highly promising signs…”

In fact, the U.S. National Library of Medicine has acknowledged cannabidiol (CBD) as having potential for the relief of “spasticity in adult patients with multiple sclerosis (MS),” but due to its wildly varying nature and seemingly random flare-up of symptoms, multiple sclerosis can still be a horrendously frustrating disease to try and treat. No two people, as they say, are affected in the same way.

And though dozens of prescription medications are available (which we’ll talk about shortly), conventional drugs can be hit or miss in terms of their efficacy for any given individual; only about 1 in 4 experience reduced MS symptoms with a prescribed pharmaceutical treatment.

This is why, in recent years, CBD oil for multiple sclerosis has come barreling into the limelight in terms of its potential as a viable treatment option. Increased marketing (as well as overwhelming anecdotal evidence) just in the past year or so has inspired thousands upon thousands of Multiple Sclerosis sufferers to ditch their prescription meds in favor of the all-natural, non-psychoactive cannabinoid.

Likewise, high-profile entities like Montel Williams (who suffered severely with MS before resorting to cannabis), have been advocating for enhanced funding and continued scientific research of the drug. Even the National Multiple Sclerosis Society, which traditionally has been a conservative organization, has jumped on board to advocate for legalized medical cannabis at the state level.

Most shockingly of all, though, is the fact that the US government currently holds a patent on CBD as a ‘neuroprotectant’, citing its scientifically proven ability to limit neurological damage from neurodegenerative diseases (with multiple sclerosis of course being a highly neurodegenerative disease).

In this article, we’ll talk about how MS attacks nerve fibers and disrupts neurological pathways, and in what specific ways cannabidiol (CBD) has been shown to physiologically manipulate and correct these pathways.

While it’s certainly no cure or quick fix by any stretch of the imagination, CBD oil for multiple sclerosis is increasingly proving to be one of the more promising treatment methods out there.

Multiple Sclerosis: What it is, what it does, and how people get it

The National Multiple Sclerosis Society defines the disease as an “immune-mediated” condition in which fibers of the central nervous system (the brain, spinal cord, and optic nerves) are attacked by the body’s own immune system.

Once the nerve fibers are attacked, scar tissue begins to form, which interrupts crucial neurological communication between the brain and other parts of the body. This communication is vital for essentially every function in the human body – motor, behavioral, emotional, or otherwise.

The severity of symptoms that multiple sclerosis victims experience thus depends on the location of the affected nerve fibers, as well as how many fibers are attacked, and how often. In milder cases, symptoms may be as moderate as mood swings or muscle spasms, while in more severe cases victims may end up with paralysis and/or a complete inability to control bodily functions.

In terms of prevalence, multiple sclerosis is a relatively rare disease; it affects about 400,000 people here in the U.S., and about 2 million more worldwide. And while researchers are still in the dark as to what exactly triggers it, they have determined that women of northern European descent between the ages of 20 and 55 are most at risk (though thousands of men also suffer from the disease).

DID YOU KNOW: Multiple sclerosis is a rare disease that only affects about 1 in 850 Americans?

Additionally, genetics and family history seem to play an important part as well in the initial onset, as does the combination of being exposed to some particular “environmental agent”, though they’ve failed to elaborate on what that agent(s) may be.

The good news, if there is any, is that contrary to popular belief the vast majority of sufferers do not experience overly-debilitating symptoms. Most, in fact, maintain normal day-to-day lives.

Also contrary to popular belief is the notion that multiple sclerosis is a terminal disease; while it is true that in some instances the disease is highly degenerative (gets worse over time) and terminal, the average lifespan of individuals suffering from multiple sclerosis is only marginally shorter than the average US adult lifespan.


Conventional MS Treatment Methods And Their Side-Effects

Multiple sclerosis exists in four different stages, or “disease courses”, and conventional treatments are prescribed depending on which particular stage the victim might be in. In order of increasing severity, the four courses are

  1. Clinically Isolated Syndrome (CIS)
  2. Relapsing-Remitting MS (RRMS)
  3. Primary-Progressive MS (PPMS)
  4. Secondary-Progressive MS (SPMS).

Given the wildly “come and go” nature of the disease, though, and the seemingly random flare-up of symptoms, people have gone untreated for months or even years in many cases before being officially diagnosed. Once diagnosed, however, common prescription meds include interferons such as Avonex, Rebif, and Betaseron, and also immunomodulators like Copaxone.

Interferons work by lowering the number of white blood cells in the body, thereby limiting the “sources” of attack on CNS nerve fibers. Since white blood cells make up the immune system and are responsible for protecting against disease, however, these drugs can be dangerous and produce side effects similar to those of chemotherapy.

| “Prescription MS drugs often present severe side effects similar to those of chemotherapy. Can CBD act as a safer, more effective alternative?”

Immunomodulators like Copaxone are generally considered to have less severe side effects than interferons, but these drugs have only been shown to be effective in about 25% of patients. Functionally, they act as “sacrificial myelin” during MS flare-ups, in which synthetically-produced amino acids take the brunt of the immune response, rather than the myelin protective coatings of the nerve fibers themselves.

When all is said and done, MS sufferers could likely care less what kind of treatment they take, or where it comes from – the only thing that matters to them is whether or not the medication is effective, and to what extent it allows them to live a normal life. Ultimately, those who seek alternative treatments like CBD oil generally do so for one of the following reasons:

  • Their prescription meds are ineffective
  • They produce too many or too severe of side effects
  • They’re too expensive

As it turns out, CBD may be a phenomenal alternative with the potential to negate all three of these factors.

CBD Oil for Multiple Sclerosis: Is it the Real Deal?

What’s so impossibly frustrating about the lack of attention and research CBD gets as a viable multiple sclerosis treatment is the fact that, as we said, the U.S. government holds a patent on the drug for its medically-proven ability to limit neurological damage.

This simple fact can be considered in one of two ways. On the one hand, the notion that the cannabinoid is recognized by the National Institute of Health as a neuroprotectant is virtually a signed, sealed, and delivered acknowledgment of its ability to treat multiple sclerosis.

On the other, more sinister hand, the fact that the drug is owned by the federal government means it’s highly unlikely it’ll ever get into the hands of Big Pharma. Superficially this might seem like a really good thing, but at the end of the day all it means is that ‘conventional’ physicians and medical professionals will never recognize it as a truly viable multiple sclerosis treatment. Rather, they’ll continue to push the risky, insanely expensive pharmaceutical drugs which are backed by FDA research and regulations.

| “Will the U.S. Government’s patent limit the likelihood that CBD gets approved as a multiple sclerosis treatment?”

At the end of the day, due to its all-powerful financial hand, Big Pharma will likely have the final say in terms of what’s going to be available in terms of treatment, and what’s not. The fact that CBD oil for multiple sclerosis has shown potential to be an efficient and productive form of medication for the disease is irrelevant – if it’s not financially viable for the drug manufacturers, you’re not going to see the majority of physicians prescribing it.

And of course, there’s nothing financially viable about a 100% natural plant that you can grow in your own home.

CBD, Multiple Sclerosis, and What you Need to Know

One thing we didn’t necessarily clarify is the difference in function between CBD and THC. THC, of course, is the archetypal marijuana component; it’s what’s responsible for getting us high, and is what has been the driving force behind generations of legal condemnation and “lazy stoner” typecasts.

CBD, on the other hand, has none of these psychoactive properties – it won’t get you any more ‘high’ than a tablet of ibuprofen will.

Rather, the molecule functions as an “endocannabinoid supplement”; that is to say, our bodies are chock-full of 100% natural cannabinoid receptors that work hand-in-hand with 100% naturally endocannabinoids – if there is an absence or deficiency in the production of these endocannabinoids, the receptors will not be able to function properly. And it just so happens that the central nervous system is the region of the body that’s most densely populated with cannabinoid receptors – the same region where multiple sclerosis attacks nerve fibers.

Could, then, multiple sclerosis potentially be a disease hinged on a basic endocannabinoid deficiency? While no one can answer that question without years of continued research, much of the anecdotal evidence is suggesting that an uncanny relationship may exist between the two components.

| “Could MS be a disease hinged on basic endocannabinoid deficiency? Anecdotal evidence on CBD use has suggested that an uncanny relationship may exist between the two components…”

For the time being, at least, it seems multiple sclerosis sufferers will continue to have to rely on self-treatment methods, and, unless they live in a medically legalized state, will have to resort to “non-conventional” approaches in order to obtain alternative medications like CBD oil.

The impossibly comical irony of the federal government owning a medically-viable patent to CBD, while maintaining a Schedule I status on the plant that it comes from, is a discussion that will have to wait for another time and another place.

Whatever means an MS sufferer might have to go to in order to receive treatment and receive the parts of their life back that the disease took from them, though, is a decidedly small price to pay in the grand scheme of things.

Current Research on Cannabis and Multiple Sclerosis

Believe it or not, dozens of academic and research publications have come out in recent years with regard to the use of cannabinoids as a potential MS treatment. Here, we point out five of the most relevant studies to date. But beware – the information contained herein may make you violently angry when considering the fact that the government has not pursued clinical trials for the use of CBD on multiple sclerosis.

Frontiers in Neurology 2017 “There is a wide acceptance of cannabis [use] within the MS community: up to 60% of PwMS victims currently use cannabis, and up to 90% would consider using it if it were legal and more scientific evidence was available.”
Issues in Emerging Health Technologies 2005 Sativex is a cannabis-based, FDA-approved medication for the “adjunctive treatment of neuropathic pain in patients with multiple sclerosis (MS).”
Neurobiology of Disease 2013 “CBD provides long-lasting protection against the effects of inflammation in a viral model of multiple sclerosis.”
Marijuana as a Medicine? The Science Beyond the Controversy 2000 “…nearly every participant in a 1997 survey of 112 regular marijuana users with multiple sclerosis [stated] that the drug lessened both pain and spasticity.”
U.S. National Library of Medicine: Cannabidiol 2005  CBD has been given a “standard marketing authorization” by Health Canada for use as a supplementary treatment for multiple sclerosis-related spasticity.

Our Top Picks: 5 Best CBD Oils for Multiple Sclerosis

As it turns out, not all CBD oils are exactly the same. While they all, of course, rely on cannabidiol as the active component, some specific tinctures have shown to be far more effective at treating symptoms stemming from MS than have others.

While a full-spectrum cannabis CBD oil is thought to be the best option, these oils are often not available nationwide. With that said, there are a few companies that seem to be helping with various symptoms associated with multiple sclerosis. Here are our top 5 favorite ones [with two extras that we had to throw in as “honorable mentions!”]:

[It’s important to understand that while they will not cure MS, these products may provide a certain level of relief]

Site Name
Our Score
Visit Site
  • Full-spectrum Hemp extract
  • No pesticides, solvents or chemical fertilizers
  • 3rd party laboratory tested
  • Price Range ($48.00 – $139.00)
5% Coupon Code: 5OFFCBD1
  • Maximum potency and purity
  • Compounded by a licensed pharmacist
  • Highly concentrated extraction process
  • Price Range ($26-$169)
  • Full-Spectrum Extract (Made in USA)
  • 100% Natural and Organic
  • Contain no artificial flavors or preservatives
  • Prices range ($48-$125)
  • CBDPure uses a chemical-free CO2 extraction process
  • 3rd party laboratory tested
  • Certified hemp grown in Colorado
  • Price Range ($29.99 – $79.99)
  • Full-spectrum Extract
  • Derived from Non-GMO Hemp
  • Ship to all 50 States
  • Price Range ($49.00 – $299.00)
  • Over 5 Years Experience
  • 3rd party laboratory tested
  • Organic hemp CO2 extract tincture
  • Price Range ($62.00 – $204.00)
  • Organic hemp CO2 extract tincture
  • Available in Cinnamint & Natural
  • Full-spectrum extract
  • Price Range ($39 - $249)

5 Best CBD Oils for Multiple Sclerosis [2018 Update]
September 29, 2018
4.8 36
  1. Lee-Anne

    Really great and helpful information here. Thank you for sharing

  2. Dani Fredericks

    Wish my doctor was more on board with cannabis treatments but like a lot of others he doesn’t give it any serious consideration

  3. Joe Trarrer

    I am not personally affected by MS, but i know a lot of people who suffer and this is really interesting to read having seen first hand the effects of things!

  4. Eleanor

    I am a retired Physiology professor from Univ of Texas. I like how this article emphasizes the fact that cannabis is not going to CURE multiple sclerosis. I have read a lot of articles basically claiming that cannabis can cure this or that, but it’s simply not true. Help relieve the symptoms? Maybe. Cure the disease? Probably not. I do think however that CBD can offer a MUCH improved quality of life and even add many years to the lifespan of MS victims. If the proper care is taken to find and use a reliable product

  5. Amanda
    I am now, a changed woman.

    As a disclaimer: I have not been diagnosed with MS. However, I am a healthcare professional, and have been tested for just about everything else. Knowing the symptoms, and the crap I am experiencing, not only would it not be a surprise for me an MS dx, it would be actually be more of a surprise if MS wasn’t it.

    Anyway, I am an academic, I love reading, I love learning. The last two years have been SO difficult for me. I already have depression/anxiety/ADHD (I call it the perfect storm). Organizing my world has been more difficult than ever. Some say it’s due to stress, but we’ve all heard that, and we know ourselves. Sometimes it’s just not friggin’ stress.

    I have been TRYING to work on my brain. I’m even taking up piano again (after roughly 20 years), just to get something going in there, ANYTHING, that hasn’t been going in a while.

    I have CBD oil for my cats, because sometimes they get a little nervous, and it’s worth a shot. Since it’s the same stuff as it would be for humans, I decided to take some down with some water. Well not too long after… Wow. Friends, I just started *sobbing*, not in a bad way. I literally haven’t felt this much like myself in longer than I can remember, and being only slightly dramatic. When you lose something so gradually, it’s hard to remember where you even started. My heart is so full right now, and I wish I could give a big hug to my brain and throw a, “Welcome Home,” party. I hope that for everyone on this site who is battling something, anything, is able to feel what I just felt. It wasn’t much, but man, it’s better than it has been.

  6. Elisha

    I will say I have tried the Hemp Bombs recently and it worked better than some of the other oils that I’ve used in the past (none that are on the this list)

  7. Laura

    Thank you for the article. MS is a terrible disease, and I know most would do just about anything to find a helpful treatment, that doesn’t have side effects.

  8. Samantha Colburn

    For those of you that don’t know, CBD is a registered patent under the US Department of Health for use as a nerve protectant. Do your homework people, THE TRUTH IS OUT THERE!!!

  9. Frank

    I truly believe that CBD has the ability to help heal and take away pain. Thanks so much for the article, I hope that more and more people start using natural cannabis for MS treatment than the dangerous prescriptions that doctors push every single day

  10. Amanda

    Actually had a teacher in high school that had MS and would talk about using CBD oil with great results. Doctor didn’t approve of it but wow that’s no surprise

  11. Shakea

    Hello all, I use cbd for my MS, anxiety and depression…(let’s just say 2018 was a *****). I absolutely love it, I use it subliminally twice a day, and the stuff works!! I live in PA and I have my appointment for my mm card in 2 weeks! I feel great on it, it is definitely worth a try! Make sure it is full spectrum cbd!!!

  12. Wil

    can’t wait til doctors start realizing this Epidiolex stuff can be used for dozens of other off-label conditions. What will they do then? Big Pharma gonna be stuck between a rock and a hard place here real soon…

  13. Dylan

    If i’m not mistaken multiple sclerosis is one of the conditions mentioned on the government patent article. No idea why more research hasn’t been put into this like with epilepsy

  14. Tonya S

    I know about the recent legalization/FDA approval for epilepsy. My question is this — where are the other approvals for multiple sclerosis, Alzheimer’s, etc??? The federal gov patent specifically mentions multiple sclerosis treatment, and at the moment insurance will not touch anything cannabis related for MS treatment. Why epilepsy and not MS? Or any other neurodegenerative disease for that matter..

  15. TK

    I started using cbd oil at the suggestion of my chiropractor while I waited for my medical cannabis card (I’m fortunate I live in a state it is legal if you have an approved diagnosis like MS). A local store carried Green Roads brand and I bought the Strawberry AK because the profile said it would help with inflammation and anxiety. Game changer. It’s also helpful for my spouse with his anxiety and ability for focus (great cognitive effect). I also use flower with thc, but I always look for a hybrid hat has a high cbd amount too. I had blood work done last week with a new dr and she was shocked that all of the inflammation and autoimmune markers were normal. In her words, she wouldn’t know that I have two autoimmune illnesses from my blood tests if I hadn’t told her.

  16. Jessica Hood

    CBD Essence is a wonderful oil to deal with sclerosis. My friend uses it regularly now and says that it’s helped her more than any other medication

  17. Mirtha Foye

    Koi CBD is highly recommended, must try!

  18. Evelyn M Decker

    Once I receive my CBS how do I take it with my MS prescription Coxpone?

  19. Sarah Nugent

    Multiple sclerosis is a terrible disease. CBD has helped my mom a great deal

  20. Siamon na

    Any body know What kind of cbd oil would you recommend for ppms, and how much should be taken daily and does it work immediate or how long does it take to show results. Thanks Siamon

    1. Rebecca G

      Very interesting article! Thank you for enlightening me. I’ve had MS since 1998 and was always able to stay 2 steps ahead of it until approximately 2-3 years ago. My relapsing/remitting MS has progressed to secondary progressive MS, and I’m about to try expensive MS drug #5. I’m going to try CBD oil, since I can no longer work, stand up like a human, and am a prisoner in my house because of the increased MS symptoms affecting my life.

      1. JB

        I was DXed w/ MS in 1985 and have taken 5 prescription meds. Status: I’ve been bedridden for over 4 years and now I also have peripheral neuropathy.

        I am beginning research on CBD now; great article!

        My brain has shrunk, cognitive decline is awful. Will CBD oil make the decline worse?

      2. April S

        Can anyone share who has MS what brand they’re using and the effects? Would love to hear your testimonials

        1. Michelle Astle

          My daughter has MS. She takes Copaxon 3 times a week and she takes CBD Oil from Hempworx. It has been amazing to see how well she is doing now.
          I joined Hempworx mainly so that I could have ready access to the oil for her.

    2. Christine

      I am curious as to why these questions which are all important, are not being answered in the reply section.

  21. Michelle Cooper

    I have tried both Koi CBD and CBD pure. Both are brilliant


    My daughter has MS, she get estavia injections every other day. These injections causes her to have extreme cold chills, she has body aches & is very tired. What should she take to alleviate these conditions?

    1. Bradley

      When I was taking my shots, I would get horrible shakes afterwards (Like I had a horrible flu), usually about 8 hours after I took the shot. So I took the shot late in the afternoon/early evening and then right before bed took a couple of Tylenol. I would sleep right through the symptoms.

  23. Jonathan Quinter

    I was just st diagnosed with MS a few weeks ago and am on a bunch of different meds and steroids. I’ve been using Charlottes Web by the Stanley Brothers and have seen drastic changes to my conditions. After 24 hours I no longer had to take 2 extra strength Tylenol everyday or my night cap pill to calm my body from the steroids. The numbness in my arm and hand have also reduced. I’m now an advocate and can’t wait to try all the brands out there. Trust me CBD is the real deal and it’s legal in all 50 states.

    1. Melinda

      Are you taking any rx meds for the MS as well?

  24. Tawnya Stokes

    Been using green roads for a while and it is quite effective. I am happy, highly recommended.

    1. Tony McCrohan

      Can you tell me which one and the dosage. My wife. has MS and are researching CBS oil. Thanks

  25. Ashley Garza

    Multiple sclerosis is a disease that can cause severe health problems later on. Cbd is the best treatment that suits me best. Thanks

    1. Jaime Richard

      I’m new to the CBD oil world and have just started researching and have several conflicting things. If the state I live in is labeled a legalized state for CBD oil for medical purposes only (Alabama) then what exactly do I need to do to get it without legal ramifications? Also, I’ve seen there are several different ways to take the oil… is one better for certain things vs another form (ex… tincture better for MS pain vs vape)

      1. Adam

        Hi Jaime, Alabama is pretty strict. Like you said CBD is allowed but it must contain no more than three percent THC to be legal in Alabama. The problem is that even though CBD possession is legal in Alabama, obtaining the drug is extremely difficult because there are no provisions for either distribution or cultivation. You’d have to either go to a different state, or order a CBD hemp oil from online stores. In regards to which one is better, check out this…https://www.marijuanabreak.com/cbd-oil-vs-cbd-vape-liquid-know-the-difference/

    2. Ike

      Hi Ashley, what brand/dosage do you find effective? My MS is not too bad (yet?) but I am trying to understand CBD oil options and am curious about your experience.

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