The 25 Best CBD Oil Brands for 2019 [Ideal for Pain Relief, Anxiety, Stress]
April 17, 2019

The 25 Best CBD Oil Brands for 2019 [Ideal for Pain Relief, Anxiety, Stress]

The Updated 2019 Guide to CBD Oil
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MarijuanaBreak Staff / Updated on April 17, 2019

It’s not easy living with pain. Whether you suffer from muscle spasms, chronic pain or arthritis finding a solution to help deal with that pain can mean the difference between a pleasant day where you can function to a nightmare of a day, just waiting to end.

Over the last couple of years, CBD oil has become a popular form of treatment for pain management. It’s currently thought to be so effective, that more and more doctors are starting to recommend. The major advantage of CBD oil compared to traditional cannabis is that it doesn’t cause the “high” feeling, and is therefore permitted in most places.

With so many companies popping up every day, we’ve done the hard work for you. We bring you the best CBD oil guide and the top 25 brands that made our list based on CBD oil quality, effectiveness, customer service and of course price. Please note, this article is updated constantly, so don’t forget come back from time to time to see the most updated information.

CBD Oil for Pain Relief

Cannabidiol (CBD) is now used globally for a variety of medical conditions including pain relief. This is following numerous studies showing that some of the best CBD oils can have an extremely positive impact on pain management.

It’s important to note that CBD oil isn’t approved by the U.S. Food and Drug Administration for any medical condition, which means that the products discussed and statements made in this article have also not been evaluated by the FDA and are not intended to diagnose, treat, cure or prevent any disease.

Even without the FDA’s review, CBD has been receiving a significant amount of attention, even being featured on some of the top news networks who have all praised its achievements.

For example, Charlotte’s Web, currently classed as one of the worlds best CBD Oil manufacturers, has been featured numerous times in the media on sites such as CNN, The Wall Street Journal and even in health magazines such as Men’s Health. They are also a publicly traded company.

CBD is one of the most fascinating additives or isolate we have discovered in recent years. Whereas most pharmaceutical medications focus on the symptoms or one enzyme or channel of the human body, CBD aids in helping a system to function more efficiently. The endocannabinoid system.
Dr. Eric Exelbert
Certified Physician

Benefits of CBD Oil

Benefits of CBD

Apart from the fact that today’s best CBD Oil drops are extremely effective, they are also very easy to take. You simply place a few drops under your tongue and they are instantly absorbed into your system. The exact consumption methods are written on the CBD oil package, and you should always consult these prior to taking CBD.

CBD Oil is known to help treat other conditions that are related to pain. For example depression, anxiety relief, fibromyalgia, and even things like fear and stress. Most importantly, those who suffer from chronic pain have claimed that it helps them sleep.

While the results from taking CBD oil will vary, many people’s lives have been changed for the better:

“I have been suffering from chronic pain in my legs for years. I often find it hard to sleep. CBD oil helps with the pain management, especially as it is impossible to obtain marijuana in my state.” – Kate Summers, Ohio

“I find the amount I’m taking has helped me a lot with my chronic low back pain and aching knees. I am taking far fewer opioids than before, and CBD oil has got me back on track.” – Jeff Freedman, New Jersey

“I had never even heard about CBD oil up until a couple of months ago. Since I’ve started treatment it has changed my life. Thank you for all the help and good vibes!!!” – Sophie Samson, Florida

How to Know if you Need CBD for Pain

To be clear, there is no one specific test, scan, or anything else of the sort that you can do to determine whether or not you need CBD oil for pain. Also, since cannabis is not yet recognized by the FDA, you unfortunately can’t really go to your doctor either and have them recommend it; until marijuana is FDA-approved, it cannot be prescribed by physicians.

So what gives, then — how are you supposed to know if you need CBD for pain? Well, ask yourself the following very simple questions:

  1. Are you in pain?
  2. Are your current medications working for you?

If the answer to these questions was ‘yes’ and ‘no,’ respectively, then some of these best CBD oils for pain may very well be a legitimate option for you. Just remember, you’re not going to get a recommendation from your physician, and therefore you’re likely going to have to take it upon yourself to make the switch.

However, switching to CBD oil from a conventional medication is far from a random stab in the dark. In fact, there was a large scale (and very well-documented) survey carried out less than two years ago that looked at precisely what percentage of patients were able to “swap” their side effect-inducing meds for a 100% natural, cannabis-based therapy.

In short, the results of the survey (which were published in the Journal of Pain Research) showed that roughly 42% and 46% (respectively) of participants claimed they were able to use cannabis in place of traditional medical to effectively treat their specific medical ailment. So if you’re wondering how to know if you need CBD for pain, remember that you’re certainly not alone.

Medical Research and CBD Oil

Medical Research and CBD Oil

Numerous studies have shown that CBD can help treat a variety of medical conditions.

A 2011 study that focused on CBD treatment for fibromyalgia, for example, showed very promising results. 56 of 112 participants who took CBD saw a great reduction in their symptoms and overall measure of pain, while those using traditional methods hardly saw any improvement.

Moreover, scientists at the Cajal Institute showed promising results in regards to CBD and Multiple Sclerosis. They used animal models and cell cultures to find that CBD reversed inflammatory responses; within only ten days, mice that were used in the study had superior motor skills and showed progression in their condition. To date, there have been well over 20,000 published scientific articles on cannabinoids and their related effects on all sorts of medical ailments.

Generalized pain, for instance, has dozens upon dozens of high profile research and clinical studies that have been carried out in universities and laboratories around the globe. One of the most well-publicized of these studies took place back in 2008, in which results determined that “cannabinoid analgesics (pain relievers) have generally been well tolerated in clinical trials … with acceptable adverse event profiles (meaning acceptable effectiveness for practical use).

Moreover, a patient survey conducted by Project CBD, declared that “…cannabis appears to be an effective pain management tool with few negative side effects.” The study went on to say that a “…significant decrease in opiate usage among elderly patients while taking medical cannabis [was observed during trial].” In short, it has been portrayed clearly numerous times through valid and well-publicized clinical studies that cannabis is a practical option in terms of efficient pain management.

And the same can indeed be said for dozens of other ailments as well. Project CBD lists nearly two dozen published studies that have been carried out on CBD as a potential treatment for anxiety, with every one of them producing positive results in favor of cannabis as a potentially efficient long-term treatment.

Why CBD is Replacing Traditional Medicine as a Pain Reliever

You are likely very familiar with the dangers that prescription painkillers (and other pharmaceuticals) present. In fact, it’s estimated that the majority of CBD oil users attempt to switch to the all-natural therapy for the precise reason of kicking prescription med habits, which all too often cause an overwhelming array of irritability, sleep disruption, digestive complications, and even thoughts of suicide.

Ultimately, the reason why CBD for chronic pain has become so incredibly popular among patients is because of the fact that it has minimal side-effects. Even highly respected entities like the World Health Organization (WHO) have come right out and said that it is “not associated with any significant adverse public health effects.”

Moreover, they have also claimed out and out that it is “not associated with abuse potential, does not induce physical dependence, [and] is generally well tolerated with a good safety profile.”

In addition to CBD’s astounding safety levels, it is also no slouch when it comes to actually reducing pain. In fact, it’s no secret that the U.S. Government holds a patent on the compound as both an antioxidant and a neuroprotectant capable of helping with conditions like fibromyalgia, ALS, and multiple sclerosis, just to name a few.

But wait, what are those so-called minimal side-effects?

Best CBD Oil for Pain: Side Effects

Truth be told, one of the biggest draws to using CBD oil for pain has been the fact that it has little distinguishable side-effects or contraindications with other medications. In fact, in a massive report that was published by the World Health Organization during last year’s 2017 Expert Committee on Drug Dependence, it was (finally) declared to the world that CBD is a “safe, well tolerated [compound, which] is not associated with any significant adverse public health effects.”

Sounds too good to be true, right?

Indeed, if you dig a little deeper you will find that CBD oil does have “one or two” potentially negative side effects. But they are minimal compared to pharmaceutical ones.

For example, one of the noted “side effects” of CBD oil for pain is dry mouth. A side effect that can be countered with an act as simple as drinking a cup of water before and after taking the oil.

Other potential side effects include low blood pressure, lightheadedness, and drowsiness, but these have typically only occurred in patients who have exceeded doses of 1,500 mg daily for a period of 4 weeks or more; far more than the average person will need take on a daily basis for chronic pain symptoms. (In fact, the majority of CBD users claim they find an effective dose to be anywhere between 10 and 40 mg daily).

In short, if you’re wondering whether or not taking CBD oil for pain will produce any negative side effects or contraindications, studies have shown and state that they are minimal. However, please bear in mind that we are certainly not physicians. This should by no means be taken as medical advice and you should do the research.

Frequently Asked Questions About CBD Oil

What is CBD oil produced from?

Most companies that produce CBD oil extract it from hemp, leaves, stalks, and flowers.

Is CBD oil Legal?

Since it started becoming popular roughly two years or so ago, the general consensus has always been that since CBD oil from top brands does not contain the psychoactive properties of THC, it is therefore legal. Unfortunately, its legality is much more nuanced because of conflicting federal laws and new court cases. What is clear is that in one of the most recent court decisions on the topic, Hemp Industries Assoc. v. DEA, which came out on April 30, 2018, the US Court of Appeals for the Ninth Circuit found that Section 7606 of the 2014 US Farm Bill (the “Farm Bill”) preempts the Controlled Substances Act (CSA), the federal law which designates marijuana as a Schedule I substance (along with heroin and cocaine) making it illegal to possess or use. This means that when there is conflict between the CSA and the Farm Bill, the Farm Bill wins out.

This is good news for the best CBD oil companies because the Farm Bill allows for the legal cultivation of industrial hemp, under certain circumstances, which can be a source of CBD. But CBD can also come from non-industrial hemp, namely the marijuana plant that most are more familiar with. Therefore, whether or not CBD oil for pain is legal can be a question of which “version” of the cannabis plant it was sourced from. If it was sourced from industrial hemp, (which contains less than 0.3% THC by volume), and it was cultivated under the Farm Bill, then it is legal.

However, if it was sourced from actual marijuana (i.e. cannabis that contains more than 2% THC by volume), then it is technically illegal. Most of the best CBD oils for pain that you find in dispensaries in states like Colorado, California, and Washington (as well as other states where weed is legal) will have been extracted from marijuana plants — not industrial hemp plants. Unfortunately, this means that these products are not allowed to be sold online and shipped across state lines to “non-legal” states.

However, like we just mentioned CBD oil for pain management that has been sourced from industrial hemp grown under the farm bill is in fact legal to buy and sell. The best CBD oil brands that we cover here on this site, claim to extract their concentrates from U.S.-based industrial hemp supplies, which if true, are 100% legal since they contain negligible amounts of THC.

The important thing is that you have to be SUPER careful when selecting CBD oils. Since the cannabis industry is not FDA-regulated, there have been dozens and dozens of companies trying to get away with selling very low quality (and even potentially toxic), “snake oils” that have been extracted using harsh chemical solvents like butane and hexane. Make sure you stay away from cheap products like these, as they could damage your health.

Do you need a doctors recommendation to purchase CBD oil?

If you are purchasing CBD that has been extracted from hemp under the Farm Bill of 2014 and contains less than 0.3% THC, it is legal to buy, sell and shop to all 50 states. This means it is available for purchase without a doctors recommendation.

How Does CBD Work in the Body?

CBD works in the body by activating receptors and neurotransmitters through a complex network of endogenous cannabinoids called the endocannabinoid system (ECS).

Unlike THC, which primarily binds to CB-1 receptors located in the brain, CBD works in the body by manipulating receptors throughout organ tissues, the immune system, the pain response system, the hormonal system, and other whole-body regulatory systems. Basically, since its receptors have been found to exist in virtually every cell and tissue type in the body, CBD is believed to work on every aspect of human health and behavior – from the subcellular level to the whole-body leve and beyond.

In fact, CBD is therapeutic in nature, and will work to manipulate bodily systems at the cellular level to return afflicted organ systems, tissue systems, and even chemical systems in the central nervous system back to a state of health and homeostasis. This is precisely why it has been capable of treating conditions such as depression and anxiety, to chronic physical ailments such as pain, inflammation, arthritis, and more.

What does CBD help with?

The FDA does not permit us to use anecdotal evidence to affirm that CBD can have beneficial (and often curative) effects on a variety of serious conditions and diseases. That being said, we have many users who say that CBD oil helps them with the challenges of:

  • Alzheimer’s disease
  • Anorexia
  • Anxiety
  • Arthritis
  • Asthma
  • Chronic pain
  • Depression
  • Epilepsy (seizures)
  • Inflammation from various conditions
  • Insomnia
  • Multiple Sclerosis
  • Nausea (emesis)
  • Obesity
  • Post-Traumatic Stress Disorder (PTSD)

How to Use CBD Oil for Pain?

Be advised that there is no single right or wrong way to go about it.

In general, the majority of people end up using higher-strength products for pain than they would for things like anxiety, stress, or depression. The majority of today’s best CBD oil manufacturers offer tinctures in three different “potencies,” usually in 100, 300, or 600 mg options. Many people start on a middle ground with a 300 mg option, and work your way up from there, but it is extremely important to consult with the brand you are purchasing from before consumption.

The key is to effectively gauge exactly how much CBD oil it takes to start managing your pain. If you start off right away with a maximum dose of a 600 mg tincture, you will have no idea how much of the product it actually took to treat your condition, and how much you wasted (this is also important because you do not want to exceed dosage and end up developing a tolerance to the active cannabinoids).

If your intention is to help treat chronic pain, then you may want to start out with a lower dose, and then proceed from there. If you notice effective results, you can downsize the dose, or likewise you can always up the dose until positive results are achieved. The key is to only increase your dosage in small increments so that you are able to pinpoint exactly how much CBD oil it takes to treat your condition. Be advised, though, that you should not exceed the recommended daily doses that are listed on the bottle and you should consult with a physician.

How to use cbd for pain

Are There Other Options if you Can’t Use CBD Oil for Pain?

Unfortunately, some people either can’t use CBD oil for pain (i.e. they may not want to hold the oil under their tongue before swallowing), or they simply haven’t found it to be effective. Fortunately, there are several other options for instance, topical CBD creams.

These are one of the most popular (and effective) choices for arthritis and other forms of localized pain and inflammation. Since the skin acts as an excellent semi-permeable membrane that “let’s the good stuff and keeps the bad stuff out,” rubbing CBD-infused creams into the affected area has proved to be quite effective in terms of both pain and inflammation reduction.

Likewise, CBD gummies and other CBD edibles are a great option that many people prefer over CBD oils for a variety of reasons (one of which is simply because they taste a lot better!). And lastly, vaping CBD oil with a vape pen has been another extremely effective method of using cannabidiol as a pain relief therapy for some users.

Before you continue to our best CBD oil for 2019 don’t forget to watch our video CBD oil Countdown.

25 Best CBD Oil Brands for Pain Relief

So without further ado, here are the best CBD oil Tinctures for pain relief based on quality, effectiveness, benefits and price:

PureKana Natural CBD Oil
Super Star
Based on 215 testers
best cbd oil

  • Full-spectrum extract, 99% pure
  • Potent, fast-acting results
  • 3rd party laboratory tested
  • No pesticides, solvents or chemical fertilizers


  • High potency oils are pretty expensive
  • No combo/bulk discounts

Official Site:
5% Coupon Code: 5OFFCBD1





Purekana Full Spec

PureKana is a unique company that has been helping thousands of patients located all across the U.S with its CBD oil drops. They have been featured on numerous major sites including HERB and High Times and were even voted as one of the Best CBD Oil brands of 2017-2019.

Unlike other CBD oils, PureKana really does excel in CBD oil extractions due to their unique CO2 extraction process which provides a near 99% pure CBD oil. PureKana Natural CBD Oil is an unflavored, dietary and nutritional supplement for increased health and vitality. It is extremely effective in treating chronic pain, inflammation, swelling, anxiety and sleep disorders.

Key Features Include:

  • Organic
  • Non-GMO
  • No pesticides, herbicides, solvents or chemical fertilizers
  • Non-psychoactive (only trace amounts of THC .05%)
  • 3rd party laboratory tested to ensure safety and potency
  • Products price range ($48.00 – $139.00) depending on potency
  • Deliver to your doorstep (All 50 states)

best pure kana cbd oil
Purekana Bottom Line
PureKana was an easy pick for our #1 choice. Our review almost unanimously selected them as having the best overall combination of potency, effectiveness, quality, purity, taste and price-to-value ratio.
5% Coupon code: 5OFFCBD1
Green Roads CBD (350 mg)
Excellent +
Based on 254 testers
Green Roads CBD Oil

  • Full range of CBD products
  • Pharmacist formulated, Worldwide delivery
  • Highly concentrated extraction process
  • 3rd Party Lab results available


  • Number of choices can be overwhelming
  • Refunds for unopened products

Official Site:





Green Roads Full Spec

Listed #2 on our list is Green Roads. This company is another powerhouse in the CBD oil industry due to their extremely effective products that provide an immediate response. The good thing about Green Roads is that their CBD oil can be consumed through Oral use or by vaping.

The 350MG CBD OIL is a sublingual and vapeable oil that is vegetable glycerin based, infused with pharmaceutical-grade cannabidiol (CBD). This medium dosage of CBD has been used by consumers suffering from epilepsy, addiction, anxiety, depression, stress, lack of focus, and pain.

Key Features:

  • Maximum Potency
  • Compounded by a Licensed Pharmacist
  • Highly Concentrated CBD
  • CBD Oils Price Range ($26-$64)

most potent cbd oil
Green Roads Bottom Line
One of the best brands on the market. We also love the fact that they now offer Terpene extracts from famous cannabis strains. This not only increases the potency of the CBD through the Entourage Effect, but also gives the oil a classic cannabis flavor.
Premium Jane CBD Oil
Based on 187 testers
Premium Jane

  • Full-Spectrum Extract (Made in USA)
  • Incredible taste, near immediate effects
  • No artificial flavors or preservatives
  • 100% Natural and Organic


  • No CBD vape oils/vaping products
  • Does not offer CBD isolate oil

Official Site:
10% Coupon Code: 10OFFCBD1





Premium Jane Full Spec

It’s been awhile since a CBD brand has turned our heads, but after receiving a few of their promotional sample products, Premium Jane simply blew us away.

One of our team members compared their 1,000 mg full-spectrum oral tincture to the Green Roads oil that he usually takes, and he said it was every bit as effective for his chronic back pain, with the effects actually seeming to last a little bit longer.

Here are some of the highlights of the brand new Premium Jane lineup:

  • Sourced from CBD-rich hemp grown under the Kentucky Pilot Research Program
  • Incredible natural flavors produced from pure Vanilla and Mint oil extracts
  • Full-Spectrum Extract packed with nutrients and more
  • Uses the same laboratory testing facility as our best CBD oil brand Pure Kana
  • Prices range from $48-$125

best cbd oil on the market
Premium Jane Bottom Line
Premium Jane may be a new company, but we had no hesitation giving them the #3 spot. They have unrivaled taste and offer some of the fastest-acting CBD in the industry.
10% Coupon Code: 10OFFCBD1
CBD Pure
Great +
Based on 173 testers
hemp oil for pain

  • Chemical-free CO2 extraction process
  • 90-day money back guarantee
  • Certified hemp grown in the U.S
  • Prices start at just $29.99


  • Limited range of products
  • No edibles, vape oils, or vape products

Official Site:





CBD Pure Full Spec

CBD Pure hasn’t received the high-profile accolades as some of the other brands like PureKana and Elixinol, but make no mistake – they manufacture one of best pain reliever CBD tinctures on the market.

Moreover, they use 3rd party lab testing to verify that every batch has perfect cannabinoid profiling, is pesticide-free, and is free of any harmful microorganisms or pathogens that may have been present as bacteria or fungi in the raw hemp material.

Here are the CBD oils that they currently have on offer:

  • 100 mg Hemp oil extract
  • 300 mg Hemp oil extract
  • 600 mg Hemp oil extract

Also, being a relatively small company you can expect that their customer service is second to none – if you have any questions at all about anything, you can get in touch with them. CBDPure offers a great product for a reasonable price ($24-$69)

cbd pure hemp oil
CBD Pure Bottom Line
While CBD Pure isn't ranked in the top 3 it is still one of the most trusted names in the industry. Excellent quality products at affordable prices.

Hemp Bombs CBD
Based on 244 testers
best cbd

  • Full-spectrum Extract
  • Derived from Non-GMO Hemp
  • Massive 66.6mg CBD per serving
  • Free shipping on orders over $75


  • CBD oils rarely discounted
  • 300mg is lowest potency option

Official Site:





Hemp Bombs Full Spec

While most CBD oil products offer up about 5-7 mg of CBD per serving (or even less than that), Hemp Bombs’ max-strength sublingual tinctures provide a massive 60 mg dose in a single dropper. For many people, this will be a more than sufficient amount to help relieve symptoms like generalized anxiety and pain.

Of course, though, they offer less potent oils than that, with a product lineup that ranges from 300 mg CBD per bottle to 4,000 mg. Naturally the 4,000 mg option is the most expensive (this is the one that provides the “bomb” 60 mg dose), as it currently sells for $299. For long-term pain and anxiety relief, though, it may be well worth it if it is effective for you and helps replace your regular meds.

Hemp Bombs is based in Tampa, Florida, and in addition to focusing on the purity and therapeutic effectiveness of their products, are dedicated to establishing themselves as a top brand in the industry with a specific target audience. One of our personal favorite products of theirs is the flavored CBD vape liquids, which are some of the best-tasting CBD vape juices we’ve ever had.

Hemp Bombs Bottom Line
Hemp Bombs is mostly known for their huge selection of vape products, but they also offer some of the strongest and most potent CBD oils on the market. Their 4,000mg tincture offers 66.6mg CBD per single serving.
Charlotte’s Web
Based on 219 testers
Charlottes Web CBD Oil

  • One of the top-selling USA brands
  • Developed by world famous Stanley Brothers
  • 15% off for military veterans
  • Offer specific CBD oil for dogs


  • More expensive than comparable products
  • Does not offer CBD edibles

Official Site:





CW hemp Full Spec

We all know of Charlotte’s Web; the miracle strain that is packed with a high concentration of CBD. The Charlotte’s Web Cannabis Strain was named after Charlotte Figi, who suffers from Dravet syndrome and was experiencing several seizures daily until the Stanley Brothers came up with this powerful strain. Since then, Charlotte’s web has been morphed into various products, including their famous Charlotte’s Web CBD oil.

Key Features include:

  • As a whole plant extract, CW Hemp Extract in MCT contains not only 500mg of CBD per bottle but also incorporates other cannabinoids, such as CBC, CBG, CBN, Amino Acids, Terpenes and Phytonutrients found in our proprietary hemp strains.
  • Charlotte’s Web hemp oil extract contains the highest-quality hemp oil, rich in natural CBD
  • Product price range – $39.99-$299.96

CW CBD oil for pain relief
CW Hemp Bottom Line
CW Hemp is no doubt one of America's best CBD oil companies, but with costs ranging upwards of $300, they are not cheap. For the price, we feel there are better options available.

CBDistillery Cannabis Oil
Very Good
Based on 206 testers
cbd for pain

  • Huge selection of CBD dabs/isolates
  • Great CBD vape selection
  • Low price options for first time CBD users
  • 99% pure CBD isolate


  • Not known for their full-spectrum products
  • Does not state source location of hemp





CBDistillery Full Spec

If you’re looking for maximum potency CBD oil for pain management, then CBDistillery’s range of tinctures should probably be at the top of your list. They use a 99% pure CBD isolate that customers have used on everything from stress to insomnia to chronic pain.

Moreover, the folks at CBDistillery are renowned as being some of the most passionate, knowledgeable, and honest in the industry. They are completely transparent and have nothing to hide in either their products or their manufacturing processes.

Check out what people had to say about CBDistillery by reading our comprehensive CBDistillery Review

CBDistillery hemp oil
CBDistillery Bottom Line
CBDistillery has built up a massive following of loyal customers, most of whom prefer the company's line of dabs, shatter, wax and isolates. For those who enjoy ultra-potent CBD concentrates, they are an option to consider.

Very Good
Based on 146 testers
best cbd

  • 100% natural, pure CBD
  • Excellent lineup of CBD vape oils
  • ISO Certified Lab
  • Complete CBD vape kits available


  • Some say flavor is too unnatural
  • Products have been known to backorder





Koi CBD Full Spec

Koi CBD prides itself on manufacturing one of the “cleanest” oils in the cannabis industry: a 99+% pure CBD tincture that has full traceability from the start of the manufacturing process (i.e. from the raw cannabis plant) to the finished product. In addition to its ISO Lab Certification status, some of its additional features include:

  • THC-free
  • Hexane and solvent free
  • Pesticides free
  • GMO free
  • Product price range – $29.99 – $99.00

Moreover, Koi has a massive range of products available; from sublingual (under the tongue) CBD oils, to their CBD vape liquids, CBD topicals, edibles, and even CBD treats for pets.

Users have claimed it to be effective for a variety of conditions including chronic pain, anxiety, stress, restless leg syndrome, memory loss, appetite control and mental clarity, just to name a few.

Learn more about KOI natural’s full range of products.

KOI CBD pain management
Koi CBD Bottom Line
Koi CBD is an inexpensive option that offers delicious CBD oils and CBD vape liquids (for those that put a preference on taste). They have good oils that can help with a wide range of medical conditions.

Elixinol CBD Tincture
Based on 209 testers
pain relief cbd

  • One of industry’s most trusted names
  • 5% of every purchase goes to charity
  • Sustainable seed-to-shelf operation
  • Sourced from 100% certified organic hemp


  • Not many flavors to choose from
  • Not the cheapest products on the market

Official Site:
Coupon Code: 10off591





Elixinol Full Spec

Elixinol has a wide range of products, but their CBD Tincture does the trick. It’s the cream of the crop regarding CBD oils and that reflects in its price. One dropper (1mg) from the 300 series contains 10mg of CBD. This allows you to get precise amounts of CBD and no guess work is required. Elixinol has received numerous awards for their products and extraction process.

Key Features include:

  • Highest strength tincture
  • Available in Cinnamint & Natural flavor
  • Full-spectrum Cannabinoid extract
  • Organic hemp CO2 extract tincture
  • Products price range ($39-$249)

best natural cbd oil
Elixinol Bottom Line
Elixinol is one of only a handful of brands over the last few years that has developed a rock-solid reputation among the entire CBD industry. If their prices were a bit lower, they would easily be a top 3 product. (Exclusive coupon code for all Elixinol products: 10off591)
CBD Essence
Based on 185 testers
best CBD Oil

  • Medicinal grade hemp extract
  • Delicious CBD oil candy edibles
  • Fast shipping + great customer service
  • Over 5 Years Experience


  • Prices start at $64
  • Only two potencies availabl





CBD Essence Full Spec

Some people say that CBD Essence’s tincture is the absolute best CBD oil for pain and anxiety, and it may just be true given the fact that they offer and “advanced and natural formula” that’s based off unique extraction processes and state-of-the-art technology — not to mention a team of pharmacists.

Their range of CBD oils are what’s called “full-spectrum,” meaning in addition to the active CBD component, they contain other important ingredients from the cannabis plant (such as terpenes and flavonoids). However, it’s important to understand that their products are 100% THC-free, meaning they don’t produce any high at all.

In addition to their range of tinctures (which come in 150, 300, and 600 mg options), they also offer hemp edibles, capsules, pastes, vape liquids, topicals, and pet care products. Price range: $62-$204 (depending on the potency).

Check out their full range of CBD options on their official site or read the complete CBD Essence Review

CBD essence pure oil
CBD Essence Bottom Line
CBD Essence hemp extract oil is a good option for those looking to save money on their monthly CBD supply, as they offer a nice bundle price when you buy four bottles at a time. Also their CBD is top-grade

There you have it. Our top 10 brands of 2019. While there are definitely some other good brands on the market, they simply didn’t come close to these leading CBD oil products. Want to find out who ranked on positions 11-25, check out our runners-up list.

Where to Start and Our Best CBD Oil for Pain Relief?

We tend not to play favorites but if we had to choose just one, we would check out PureKana
Not only have they managed to help thousands of patients, but their customer support and product is top of the range.

While the other CBD oil stores have high-quality products, our choice simply came down to variety, potency and price. Whichever you choose to go for, though, know that all of the companies above have an outstanding store and offer a wide range of effective products, from CBD oils to Terps and even CBD creams. Plus, most have a 100% money back guarantee policy, which is quite nice!

Green Roads CBD

  • Full range of CBD
  • Pharmacist formulated, Worldwide delivery
  • Highly concentrated extraction process
  • Lab results for all products

Shop now
Purekana CBD Oil

  • Full-spectrum extract, 99% pure
  • Potent, fast-acting results
  • 3rd party
    laboratory tested
  • No pesticides, solvents or chemical fertilizers

Shop now
Premium Jane

  • Full-Spectrum Extract (Made in USA)
  • Incredible taste, near immediate effects
  • No artificial flavors or preservatives
  • 100% Natural and Organic

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CBD Pure

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  1. Paula Bohl
    Need help!

    I have neuropathy in my feet and I need relief am I at the right place

  2. Ryan F.
    Fantastic list, spot on

    Really impressed by the comprehensiveness of this list, thanks to MB for taking the time to put this out there. I was in the process for awhile of getting into the industry, and will say that in my experience as well these are the top brands out there – especially the top 5 or so. Really can’t go wrong with any of them. Thanks again guys and cheers

  3. Debbie
    Thank you for your time and reaschearing for me, I'm counting on it to be factual and choosing from here..

    Thank you so much for this thorough information and your time to give me the power to make my right choice..usually I spend hours, days, weeks to research things like this for my anxiety and pain of another without strong drugs and avoidance of others..I’m putting all my trust into your information which I never do..I hope I’m right because these benzos and 2 others are not helping and not my answer for stopping this uncontrollable feelings I have from getting any quality of life in the simplest way…I’ll be back if I find out these statements are not true…but right now I’m going to decide which one is best for me…thank you…Debbie. Ventura Beach, Ca

  4. Jame R

    Not sure if is the CBD or it is just a placebo effect but I definitely feel much better lately. Thanks for a great post

  5. Smokestack
    Drug test safe CBD vape?

    So, I’m a truck driver who has trouble sleeping. I feel that CBD would help me, just as weed always did before. My biggest concern is that I can be drug tested at the drop of a dime, and they only do hair follicle tests. I would love a CBD Vape that would work for me.

    1. Marlene
      No "Dirty Urine" With CBD Oils

      Dear Smokestack, the truck driver. I have researched your concern and what I have found is that CBD Oil will not give you a “dirty urine” unless you take more than the recommended maximum dosage, AND for a long period of time. I think you will be very happy with using CBD Oils! 🙂

  6. Odette Luther
    Just wanted to know how should you feel when I’am taking it for epilepsy that i get numbness on my hands and get spells that i don’t remember if I’am standing or sitting down

    How can you tell if it is working and how you should feel I have epilepsy. I get hand numbness and spells that i don’t know I’am having it doesn’t happen a lot. I take 10 drops 2 times a day. Should i increase how many drops to take

    1. Adam
      Speak to a mmj doctor

      You should really get professional advice.

  7. Dana Brown
    2 years and going

    I’ve been using cbd for back pain for the past 2 years. it has changed my life. I used to find it so hard to get out of bed. Amazing medicine and I think people that don’t understand its potential are living in the past.

    1. Patricia

      What do you use?

    2. Jo
      First time user

      Hi…..I have had lower back pain since I had my kidney removed last year. Nothing seems to work. How much do you take, and what mg.

  8. Geanette
    Great Information!

    Thank you for the information. Very helpful.

  9. Marie Roman
    CBD from GreenRoads

    I am of the opinion that we must not live in pain with CBD around. It is a natural substance, with negligible to no side effects and helps in pain management. The cost is also not too high if we compare it to very strong analgesics which really have harmful effects on the body. I myself use this for chronic arthritis and recommend it around as well. CBD from greenroads is the one of my choice.

  10. Karen R
    Excellent roundup

    Very well written. Thank you for all the information.

  11. Linda Alvey
    What’s the best way to take it for pain sublingual or does it matter.

    I had a very serious back injury 11-18 I gave and surgery in Jan.that turned in to 4 I’m as good as I’m going to get my doctors recommended the full spectrum it helps but not like the made out that it would .what is the best way to take it subliminal or just put it in my mouth please help.

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