5 Best Cannabis Strains for Instant Migraine Relief

Effective Marijuana Treatments

Marijuana Treatment, Strains, Migraines

Most of us suffer every now or then from a headache, but when a migraine attacks, it’s an entirely different ball game. Put aside the throbbing head pain, nausea and vomiting, one of the biggest problems is that when a migraine sets in, it feels as if you’ve gone head-on with a semitrailer. It can completely wreck your day, disabling you from doing anything.

Sure, migraines won’t kill you. Instead, they’ll just torture you enough to wish they did. According to some migraine sufferers, “A migraine has a life of its own.” – The only problem is that it takes your life along for the ride.

Are All Migraines Alike?

The textbook definition of a migraine is a severe, painful headache that can be preceded or accompanied by sensory warning signs such as flashes of light, blind spots, tingling in the arms and legs, nausea, vomiting, and increased sensitivity to light and sound.

In the U.S., more than 37 million people suffer from migraines, and it is estimated that 13% of adults in the U.S suffer from migraines. They are more common in women than men and can last anywhere up to 72 hours. Unfortunately, there are those that suffer from chronic migraines, where the symptoms can last for more than 15 days a month.

One thing to note is that each sufferer will experience a migraine in a different way. This means that a migraine you experience will be entirely different to your next door neighbor’s one, cousin, sister or best friend.

While the exact cause of migraine headaches is unknown, people who suffer from migraines can clearly identify certain triggers.

Migraine Triggers

  • Allergies – These can be seasonal or even allergic reactions.
  • Irregular environments – Such as bright lights or loud noises. Party lights and even strong smells have been known to trigger migraines
  • Stress – This can be any type of stress. Work related, depression, tension, and even physical stress.
  • Sleep – We all need our beauty sleep, and there is a reason for that. Tiredness, jet lag or irregular sleep is known to lead to migraines.
  • Change of diet – Migraines sufferers claim that when they skip a meal, eat too much or too less of something (chocolate, nuts, bananas), it will trigger the start of a migraine. Specific foods that contain tyramine (smoked fish, figs, beans) or nitrates (salami and bacon) are also known to trigger the pain.

According to Migraine.com, 65% of chronic migraine sufferers reported that depression was a comorbidity.

Marijuana Treatment Migraines

Migraine Treatments Cannabis and Conventional

Combating a migraine is a difficult task as once it sets in it’s normally a question of locking yourself in a dark room and waiting it out. Traditional medications have been developed to treat migraines, including pain relievers (Aspirin or ibuprofen), Triptans (Frova and Imitrex), Egrots and last but not least the dreadful Opioid medications which contain narcotics (codeine).

Sounds terrible, right?

Well stay positive, stay strong as there are alternative solutions.

According to leafly cannabis has been used as a migraine treatment for years but is only now coming into the light. A marijuana study published by Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of Colorado recently revealed:

  • Out of 121 adult participants, 40% of subjects reported positive effects.
  • The average number of migraine headaches decreased from 10.4 per month to 4.6.
  • 85% of subjects reported having fewer migraines per month with cannabis.

The reason behind this is because weed is known to have short-term health benefits that can help control a variety of things including relaxation, pain relief, sleep and as many of you probably know – appetite.

Do all Cannabis strains have a positive effect on our brain?

Heavens no and it is best to consult with your medical marijuana physician before choosing the cannabis migraine treatment route. Some marijuana strains will even have the opposite effect, causing your heart to race, initiate allergic reactions and cause symptoms which could have the opposite effect and lead to a migraine.

CBD Oil Discount

If you suffer from migraines and have access to medical marijuana then it could be a solution for you. But with so many different cannabis strains out there, where is the best place to start? Thankfully, we’ve done the ground work for you. Here are the 5 Best marijuana Strains for Instant Migraine Relief:

Medical Marijuana, Migraine Treatment

OG Kush Marijuana Strain

This cannabis strain is quite common and can be found in nearly every dispensary. The reason why it’s at the top of our list is not because it looks pretty but because it has powerful sedative effects. This cannabis strain really takes off the edge and also helps to combat symptoms associated with migraines. OG Kush is a hybrid cannabis strain that contains 20% THC, which will take your mind off your migraine. As most of you probably know, THC has a wonderful effect and can help with different medical conditions.

Why is the OG Kush Cannabis Strain Good For Migraines?

OG Kush will provide you with a double effect of relief and happiness. Due to its high THC levels it will give immediate relief but the CBD will help to support reducing the pain long term. With this cannabis strain it is important to catch the migraine before it become full blown.

ACDC Marijuana Strain

This is a great cannabis strain for those of you who want a solution but don’t want to get high. ACDC is a high CBD strain that is Sativa dominant. ACDC has a 1:20 THC/CBD ratio, with CBD levels that can reach as high as 19%. It is known for reducing inflammation, which makes it effective at reducing the symptoms of migraines. ACDC is a great cannabis solution for combating anxiety and depression. Furthermore, due to its low THC content, a psychoactive high will never occur. Plus if you smoke this strain while listening to the band, you’ll receive a double dose of joy and relief.

Why is the Cannabis Strain ACDC Good For Migraines?

ACDC is rich in CBD. It is a strange but pleasant cannabis strain and has a sweet and earthy scent. It provides a happy and calm feeling which is perfect for treating chronic pains such as migraines. This strain is also used to treat anxiety, multiple sclerosis, seizures, nausea, tumours and tremors.

Related Article: How to Increase CBD When Growing Weed

Harlequin Marijuana Strain

Harlequin is a 75% Sativa dominant hybrid that has a 5:2 CBD/ THC ratio. It usually has about 4-7% THC and 8-16% CBD and produces the feeling of clear-headed and alertness which may help you get through your day. This cannabis strain is very helpful for people that have high levels of pain associated with their migraines as it has a balance of THC and CBD that allows for good pain relief without an intense high. Harlequin is also known to be relaxing, but non-sedative.

Why is the Cannabis Strain Harlequin Good For Migraines?

Similar to the other cannabis types, this one will do the trick. Harlequin should be used before the migraine becomes full blown so that the impact of the THC and the CBD can do it’s magic. The THC will leave you mildly buzzin’ and the CBD (depending on the CBD levels), will help with the pain.

Purple Kush Marijuana Strain

Some migraines are so bad that the only solution is to relax and wait it off. Most suffers say that sleep helps. Purple Kush is a great solution for that as it induces a numbing sensation that is bound to put you out for the count. Purple Kush is a pure Indica strain that emerged from Oakland after cross breeding Hindu Kush and Purple Afghani Cross. It contains 17-22% THC and 0.07-0.1% CBD.

Why is the Purple Kush Cannabis Strain Good For Migraines?

Apart from making you smile when you look at this beautiful strain, it’s ingredients will do wonders, if used correctly. This strain won’t have the same effect as the other high CBD strains and its powers rely mainly on its THC content. The THC will soothe the intensity of your migraine as long as you are experiencing the euphoric high. This strain is best used before bed or if you have the time to relax and wait off your migraine.

Related Article: How to Grow Purple Cannabis | The Complete Guide


As the name says it, this Indica marijuana strain is a powerful remedy for migraines. Similar to ACDC it contains barely any THC and normally has around 15% CBD. Remedy is known for producing a relaxing, mellow feeling which is sometimes exactly what you need to combat a painful migraine.

Why is Remedy Good for Migraines?

You won’t find this strain in every dispensary but it is one that should be on your list. Similar to all strains, you should try to catch the migraine before it knocks you out for the count. Remedy is a strain that will instantly combat your migraine but won’t put you out of action.

But Wait…

What if you don’t have access to medical marijuana, are there other migraine solutions?

Marinol for Migraines

This is not a solution we recommend but something that we had to discuss in this article. In 2004, big Pharma came up with a synthetic version of THC and released Marinol to the market. Since then it has become the primary drug used for migraines, along with Sativex.

Marinol is a basically an industry developed THC that is dissolved in sesame oil. Marinol is very similar to THC, but one is natural and the other is not. It is used for a variety of medical conditions including HIV/AIDS, Cancer and more…It is listed as a Schedule III substance, which is crazy when you think about it, as it will make you as high as a kite. Much more than natural THC. Unless of course you are smoking some 80% THC strain.

While it may be a solution for some, it is given only with a prescription. Just remember, it is a pharmaceutical product and it is synthetic. Our advice, stick with the real thing if you can.

Related Article: 3 Ways to Get a MMJ Card Online (in Minutes)

Final Thoughts About Cannabis as a Treatment for Migraines

Does this mean that you should rush out to your local dispensary and pick up a few cannabis strains? Definitely not! Marijuana consumption should be done responsibly. Whenever you are trying new strains, make sure you start off slow and similar to all new things it’s best to consult with a professional.

5 Best Cannabis Strains for Instant Migraine Relief
April 19, 2017
  1. Mary Donohue

    I have had intense migraines for the past 4 years. I started off with a migraine once a week and now get 2 migraines every single day. My doctor refuses to give me anything, but Triptans (capsules) and Advil to alleviate the pain. I have tried Topamax, Elavil and Pamelor. Nothing has remotely worked. I now take 2–100 mg of Sumatriptan tablets a day and approx. 5 tablets of 200mg of Advil. I have never abused drugs in any way and see headache specialist. I really do not understand the reluctance to properly treat my pain. I live in NY. The pain is intolerable and would kill myself, but I am afraid I would not do it correctly and end up in a vegetative state and still have MIGRAINES. I am desperate and will try anything at this point. I just cannot live with this pain anymore. It feels as though my brain is going to explode through my skull. It is severe pressure. I have had multiple MRI’s of my brain, lumbar punctures, MRI of my spine (yesterday) as my the pressure of my lumbar puncture was on the low side–7. I am hoping there is a problem with my spine leaking cranial fluid.. as SOMETHING might be able to help me.

    1. Adam

      Check out this https://www.marijuanabreak.com/medical_clinics/nuggmd-new-york-the-complete-review

    2. Leanne

      Hi im a Kinesiologist with history of 22 years migraines i know how you are suffering. Please seek a naturopath or kinesiologist someone who specializes in body cleansing of toxins and parisites. Chances are your loaded with toxins and parisites. Theres parisites the docters cant find because they nest up in your liver. Seek out a kinesiologist or Touch for health practitioners in your area. It could change your life. Im so sorry your suffering. Cbd oil and thc oil helps alot so see your docter or ask who is licenced to prescribe mm,get applications for medical marijuana and try it along with a detox program. Dont give up i know the suicidal thoughts and the despair. Take my advice and see your life change !!! Prayer and faith will help too! Take care and start taking care of you.

  2. eduardo

    i have migraine since i was 2 years old, im 28 now, and after all the treatments with medicines, i started to smoke some INDICA, and feeling better each week. I m from brazill, the problem is that weed here is horrible, so we have to buy it from uruguay that now has legalize it the marijuana.

  3. Nancy Stallings

    Harlequin is superb, I bought it last week and the results are great.

  4. Quiet Fox

    I use “cookies” made from an unknown sativa strain (seeds donated, grown with lots of fertilizer, very strong) cooked into herb butter for making them. Find regular use, one cookie every two days, eliminates migraines. If I don’t eat my cookies for a week or so the migraines come back. Canadian government previously did not recognize migraines as legitimate to treat with cannabis. Waiting until pending legalization to apply for medical use. Don’t smoke, turn green and cough a lot. Cookie recipe perfected over the years.

  5. Nancy Wilkerson

    My favourite is sour diesel. It is an amazing product and has helped me tremendously.

  6. Amy Sloane

    Are there medical marijuana edibles? I don’t really want to smoke every day. I have chronic migraines. Thanks.

    1. Adam

      Have you tried gummies or the oils?

  7. Winnie Font

    Bought Purple Kush and ACDC, let’s see which one is better.

  8. Kim

    After reading this article and related comments, I am wondering do you all smoke? Do you use oils? Is there any edibles out there that you have found that works? We have a long family history of migraines and daily headaches. Any info you want to share would be helpful.

  9. Amanda Perkins

    ACDC is the perfect strain. It keeps me calm and is very effective for relieving migraines.

  10. Allison Anaya

    Need some powerful medicine for my head. Please could you suggest some for me.

  11. Phyllis Bennett

    I have read everyone of the comments on this page. I have had migraines since I was 12. My first one I thought would kill me! I have had every test and scan known to man ! Been on everything from aspirin to topamax and morphine. Currently I am on staydol a derivative of morphine. It sucks! I’m now researching cannabis. Looking for the best strain for pain and nausea. I am now 47 years old plagues with these torturous migraines about twice a month.

    1. Michelle Bennett

      I have had more success with Indica for migraines. sativa makes them worse. hybrids work well but it’s a matter of experimenting. I started migraines very young as well. I was on beta blockers as i was getting 24 migraines a month. then, i got both my daith pierced which eliminated my need for beta blockers but I still got about 8 per month. with daily indica my migraines are at less than 2 per month. o do purchase the oil also and make edibles. these work wonderfully but it takes an hour to kick in. I’m 44. I have a medical prescription.

      1. Cairy

        India works better for me too! All I read says sativa sativa sativa. I don’t get it. Sativa make me way worse. Dizzy. Nauseous. It’s horrible. But indica is a wonder drug. I have daily hemiplegic migraine. Glad to see someone agrees.

    2. Weedyneedy

      Wow, you are telling my story. I went to one doctor who blew me off as a hyper female. After tests were done, he said I had 65% scar tissue on my brain. He was more of a human being after that. I live in Texas, and I can’t believe my options are to move to another state and leave My Family so I don’t have to live a tortured life. Really praying for a

  12. Melissa Greer

    OG Kush is the strain I use to keep a headache at bay.

  13. Eleanor Hale

    Migraines are super easy to treat with CBD. Happy with the results

  14. CA

    My daughter is a chronic migraine sufferer and has been on topamax for years. We have started looking into CBD for her to get some relief. Are there any CBD’s available that do not have THC?

    1. Adam

      Check out the site, there is tons of information on that topic.

    2. Stacey

      Yes there are cbd with zero thc…

    3. IamabudtenderinWA

      Its hard to find pure cbd.. But you can find it. I noticed some at the feed store the other day. For dogs. Non flavored. Is the same
      For humans. If u r in a legal state u maybe able to find some tincture with out thc in a dispensary.
      Good luck

    4. Katie Comens

      Yes! There is a CBD oil called Charolettes Web that I believe is 100% CBD and can be purchased online. It was developed to treat epilepsy in children.

  15. Brandi Wagemann

    What happens if the opposite occurs? My father suffers from debihilitating migraines and has tried edibles to no avail. However, I found out tonight that he has been on topamax for migraines for years and just recently stopped taking it. How long does it take for topamax to get out of your system? He started with the synthetic drops which he said brought on a mild migraine. He then tried the real deal with same result. I for one have said that he isn’t giving it enough of a chance to work. So if someone out there can answer the question above that would be most helpful.

    1. Adam

      In regards to Topamax as far as we know the half-life of Topamax is reported at 21 hours. This is the time for 1/2 of the amount to flush out your system.
      So basically every 21 hours, 1/2 would disappear, then 1/4, 1/8, 1/16 and so on… Generally speaking, physicians use a period of time equal to 5 or 6 half-lives as a measure of when a drug has cleared.
      In regards to the migraines, it could be something in the drops or the extraction. Which drops you using?

    2. Lou

      As far as what strains or products to use for your dad, defiantly try AC/DC mixed with Blue Dream. About 2/3 AC/DC to 1/3 blue dream. It’s best in a vaporizer like Silver Surfer (table top) or Grasshopper (portable). Have your dad use the vaporizer with that mix right at the beginning of a migraine. The relief should last a good two to three hours. When it begins to wear off have him medicate again and continue to do so. He should find that the migraine has subsided after three or so uses.

      Also, a brand called Mary’s Medicinals makes transdermal patches that last 12 hours. These are a life saver for someone with any sort of chronic pain including migraines. I have found the CBN patches to be the most helpful for pain, plus there’s no high with those, but others like the CBD/THC combo patches for pain. Get a couple of each and see what works best for your dad. Good luck to you both!

    3. Michelle Bennett

      try indica. the strain is important. even indica with a small amount of CBD works well. sativa makes my migraines worse. unfortunately, it’s a lot of trial and error.

      1. Adam

        That’s right.

  16. Cindy

    I am a chronic migraine sufferer..I’ve gone through so many medications and none work..I’ve never done drugs of any kind..but after 2 yrs of daily migraines I’m desperate..how do you get these drugs..I don’t live in a State where marijuana is legal

    1. Cindy Wolfe

      I have had migraines since my twenties related to hormonal imbalances, stress,etc. Occipital neuralgic headaches eventually developed and were daily by 1990 which progressed to 24 HOUR pain by 1992. This required a termination and early retirement from my intensive care nursing employment at age 57..
      It was later derived -after countless neurologists/ neurosurgeons and multiple hospitalizations – that I was suffering from a cranial nerve (c3-4) occipital neuralgia possibly from multiple concussions ( ski competitions in my 20’s). I’ve had 4 neurostimulators inserted and replaced, receive Botox every 3 months, on topamax and methadone ( 5 mgs b.i.d). I would love to try cannabis…

      1. Snowdays

        OMG. My hearts breaks hearing all u went through. I hope you have found some relief. I get them frequently. It’s torture.

  17. Patricia Carter

    Migraines are torture. Cannabis is the savior

  18. Kelly Kuntz

    I suffer from Migraines constantly. Some days it is terrible. I just want to get relief. Please suggest me the strain which I can purchase to get relief from such throbbing pain.

    1. Syn

      Catatonic, ACDC, Harle-Tsu, Sour Diesel, Strawberry Banana is good but will get you high, the others I named won’t.
      Sour Diesel seems to work good for me and seems easiest to find. I have migraines every day so I know about having them constantly.

  19. Dawn Cody

    Migraines today have become a common problem. People suffering from a migraine know very well how it can ruin their life. I am also one of those and the OG Kush marijuana strain is the ideal remedy.

  20. Addie Halliday

    I don’t know if I would only use CBD as a treatment but it sure does help.

  21. Alice Ingham

    Acdc strain is definately an awesome strain and helps with migranes. Wonderful results

  22. Socorro Fulcher

    There is a tingling feeling in my arms and legs, I think I have developed migraines. can I take marijuana on regular basis? please help

  23. James

    Cannabis certainly has a lot of medical benefits and can provide relief for migraines. The available clinical evidence and anecdotal reports are fascinating and hopefully, we will continue to hear more success stories of patients on their path to recovery.

  24. Lydia R. Barros

    Migraine is a torture I have been suffering my whole life but harlequin cannabis strain is the best thing for me. Must try once.

  25. Sherry

    Migraine is a killer but thanks to purple kush cannabis strain. It is perfect as it gives a numb feeling making the patient sleep and sleep is always good for migranes.

  26. Kelley

    Due to irregular sleep, I developed migraines. But thanks to cannabis strain that gave me instant relief.

  27. Ellen

    Migraine is bad but thanks to Indica marijuana strain, it eases down the pain and gives a relaxed feeling. Really a great remedy to fight with severe migraines.

  28. Sharon K

    After reading this article, I had harlequin. Since the pain had just started, it worked perfectly. The THC and CBD did wonders in lessening the pain.

  29. Peggy

    Cannabis works wonders to cure my migraines, really bad to have this extreme headache. But purple kush is great for me at bedtime.

  30. Sammy

    I’ve been suffering from migraines all my life. Not the ones where you can’t move, but still when I get one it hurts. Weed really helps deal with the pain

  31. Kate

    Thanks for the info, should help next time I experience a migraine attack

  32. Aiden

    I have been suffering from Migraines for years. OG Kush works best for me

  33. Sophie

    Tried 2 out of the 5. Remedy worked well the last time round but it’s hard to get

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