5 Best Cannabis Strains for Restless Legs (Updated)

If you have unusual sensations such as crawling, prickling or aching in your legs when you sit still or lie down, or find it almost impossible to resist the urge to move them, it’s likely you have Restless Leg Syndrome (RLS). As well as being common in pregnant women, it is a surprisingly regular problem amongst Americans with up to 10% of people suffering from the issue.

In this article we will explore the different treatments available for RLS and discuss how specific marijuana strains are helping millions of people worldwide.

What is Restless Legs Syndrome?

The condition is sometimes known as Willis-Ekbom disease and is a nervous system issue that results in an overwhelming urge to move your legs. It typically causes an unpleasant creeping sensation in your calves, thighs, and feet and the problem is usually at its worst at night. In rare cases, the arms are also affected.

While it is not a serious condition in itself, restless leg syndrome could be a symptom of a larger problem. Doctors usually conduct a blood test to see if there are any underlying issues.

What Causes Restless Legs Syndrome?

In the vast majority of cases, there is no obvious cause for the condition. In these instances, it is known as primary, or idiopathic, restless legs syndrome and it can run in families. Some neurologists believe restless legs syndrome could be a result of how the body handles the chemical, dopamine.

This chemical plays a role in controlling the movement of the muscles and could potentially be responsible for the involuntary movement of the legs associated with restless legs syndrome.

It is worth noting that in some instances, restless legs syndrome is the result of an underlying health condition such as kidney failure or iron deficiency anemia in what is known as secondary restless legs syndrome. Specialists have yet to come up with a satisfactory reason why the condition is so common in pregnant women. However, it usually disappears soon after giving birth.

What Are The Symptoms of Restless Leg Syndrome?

  • Sufferers of restless leg syndrome report the following:
  • An unpleasant creepy-crawly sensation.
  • A painful cramping sensation in the legs, often in the calves.
  • A feeling as if there is sparkling water inside the blood vessels of their legs.
  • An itching, throbbing, burning or tingling sensation.
  • An irresistible urge to move their legs.

The severity of the condition varies from mild to completely unbearable. It is interesting to note that women suffer from restless leg syndrome twice as often as men.

If you have restless legs syndrome, there is an 80% chance you also suffer from periodic limb movements in sleep (PLMS). If you have this particular condition, your leg will jerk or twitch uncontrollably. It usually happens at night when you sleep, and in many cases, the twitching and movement will cause you to wake up. The movements are relatively brief with episodes lasting from 10-60 seconds.

What is Life with Restless Legs Syndrome Like?

While it may seem like a relatively minor complaint, restless legs syndrome can have serious long-term health consequences if it interferes with your sleep. As well as preventing you from operating at full capacity, lack of sleep increases your risk of suffering from other medical conditions such as diabetes, heart disease, and obesity.

A lack of sleep also damages your immune system and makes you more likely to become ill. According to a variety of studies, people who sleep less than seven hours a night gain more weight and are at a greater risk of becoming obese than those who sleep more than seven hours. The above is just the tip of the iceberg. Lack of sleep results in loss of sex drive, reduced mental capacity, depression, anxiety and much more.

For individuals that suffer from restless legs syndrome, night time can be a miserable experience. They spend several hours tossing and turning as the unpleasant sensation in their legs take hold. This issue could happen just once a week, or it can impact sufferers practically every night.

Traditional Ways to Treat Restless Legs Syndrome ( Not Marijuana Related)

Traditional Ways to Treat Restless Legs Syndrome ( Not Marijuana Related)


If the condition is part of an underlying medical problem, treating that condition will normally get rid of the issue. Otherwise, the following treatments are regularly used.

Heat, Cold, Massage

You apply heat, and cool packs to the muscles as alternating heat and cold can sometimes alleviate the aches and pains associated with the condition. Another remedy is to have someone massage your lower legs just before bedtime.

Relaxation & Exercise

Regular exercise such as brisk walks and leg stretches could help. Likewise, scheduling some relaxation time before bed could reduce the symptoms. Options include tai chi, meditation, and yoga.

Adopt Better Sleeping Habits

First and foremost, create a sleep schedule and stick to it. That means going to bed and waking up at the same time. Develop a bedtime routine designed to relax you before going to sleep. Read a book, take a bath and stay away from electronic devices!

Related article: 4 Best CBD Oils for Sleep and Insomnia (2017 Review)


First of all, make sure you’re taking your vitamins because lack of folic acid, iron, magnesium and vitamin B are associated with restless leg syndrome. You can also try over the counter medication such as naproxen, ibuprofen or ketoprofen. Prescription medication such as muscle relaxants could help, but in many cases, they don’t relieve the leg sensations and also cause drowsiness during the day.

Medical Research on Marijuana for Restless Legs Syndrome

Research about the use of marijuana for restless legs syndrome is relatively new, and there isn’t enough volume to draw conclusions just yet. However, the early signs are encouraging. A 2017 study by Megelin and Ghorayeb used CBD on six patients who suffered from restless legs syndrome. Every one of them reported a significant improvement in their sleep quality.

The aforementioned link between restless legs syndrome and dopamine has also been investigated at length. A 2017 study by Stampanoni et al. on the impact of cannabinoids on Parkinson’s Disease once again showed that the cannabinoids found in marijuana interact with CB1 and CB2, the endocannabinoid system’s cannabinoid receptors, to control the release of dopamine. If there is indeed a link between dopamine and restless legs syndrome, CBD could be used to regulate its release and bring a halt to the symptoms.

5 Best Marijuana Strains for Restless Legs Syndrome

5 Best Marijuana Strains for Restless Legs Syndrome


1 – Granddaddy Purple (Indica Marijuana Strain)

Granddaddy Purple (Indica Marijuana Strain)


This Indica dominant marijuana strain is almost a ‘knockout’, so we don’t recommend taking it during the daytime. However, take Granddaddy Purple before going to sleep, and you’ll find it extremely hard to keep your eyes open! Seriously, it makes your eyes feel heavy in a hurry and if you’re already tired, say goodnight! Its THC level is 17-27%, and its CBD level is 7%.

2 – Holy Ghost (Hybrid Marijuana Strain)

This is a hybrid marijuana strain with 50% indica and 50% sativa. Its THC content is 28% so be prepared for lift off! Holy Ghost provides you with a focused high that gives you energy after about 10 minutes of ‘couch lock.’

3 – Purple Kush (Indica Marijuana Strain)

Purple Kush Strain Review


Purple Kush is a pure indica marijuana strain with a THC content of 22%. It routinely figures in ‘top 10 most powerful strains in the world’ lists, and it rewards users with a euphoric head high that eliminates any feelings of pain. The high spreads throughout the body and leaves you feeling sedated.

4 – AC/DC ( Hybrid Marijuana Strain)

ADCD Cannabis Strain

This is another 50:50 hybrid, and unlike other entries on the list, ACDC cannabis has a relatively low THC content (1-6%) and high CBD content of 20%. It has a strong effect on the whole body but enables you to concentrate at work, so it is worth taking during the day if restless legs syndrome strikes you as you sit down.

5 – Afghan Kush (Indica Marijuana Strain)

Also known as Afghan OG, this indica marijuana strain contains 21% THC, 6% CBD and 1% CBN. It provides your body with a calming feeling and relaxes the muscles. The impact can last for up to three hours which is plenty of time for you to get some sleep!

Final Thoughts About Marijuana For Restless Legs Syndrome

Although research is still in its embryonic phase, there is already evidence to suggest that marijuana is capable of eliminating the effects of restless legs syndrome. It can relax the entire body and help you get some much-needed sleep.

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