5 Best Marijuana Strains for Neuropathic Pain [Updated]

Neuropathic pain, commonly referred to as nerve pain, is experienced by many people. It’s a complex condition that is estimated to affect nearly 20 million Americans. It may be chronic or temporary, debilitating and intense, or just plain aggravating. People who struggle with conditions like HIV, diabetes, and fibromyalgia often experience neuropathic pain, while medications, injuries, and infections can also be to blame.

Neuropathy is described as damage to the motor, sensory, or autonomic nerves that results from an underlying cause. It’s a painful condition that affects various parts of the body and results in weakness and numbness, along with pain. The pain is often described as a burning, tingling, or stabbing sensation, and it can be extremely agonizing.

In recent years cannabis has been shown to provide relief of neuropathic pain for patients who are unresponsive to conventional medications. This is primarily due to the relationship that marijuana has with our endocannabinoid system. When medication no longer provides the desired relief, marijuana has the potential to target specific nerves that are responsible for the pain.

The peripheral nerve receptors that are responsible for regulating pain sensations, mood, appetite, and memory are known as cannabinoids. When CBD or THC enters the body, they activate cannabinoids receptors, which then work by regulating the neurotransmitters and ultimately reducing pain levels. Studies have shown that a short-term, low dose use of cannabis can lower the intensity of pain and also improve sleep patterns without impairing cognitive function.

We all know that you can get many different types and strains of marijuana that are effective in treating different conditions. This leaves us with a very important question. What are the best strains for treating neuropathic pain specifically?

Blue Dream

Cannabis Strain #2 - Blue Dream


A rather potent cross between the ever classic strains Haze and Blueberry, Blue Dream is a sativa-dominant hybrid that has really made a name for itself in the medical community. Perfect for daytime use, it’s become especially popular for those who suffer from pain. It has a relatively high THC level that averages between a low of 17% and a high of 24%. The CBN and CBD levels reach 1% and 2% respectively.

The Blue Dream strain induces uplifted, happy, cerebral euphoria, as well as extended pain relief without heavy sedation. Along with promoting good pain control, it could also help to alleviate depression and reduce stress. With a sweet berry aroma and flavor, it’s known to be a very pleasant and delicious tasting strain.

Jack Herer

Jack herer marijuana strain

Jack Herer originates from the popular sativa strain Haze, crossed with Northern lights and Shiva Skunk to provide strong indica properties: It’s well known as nature’s painkiller. Originating in the mid-1990s, it was bred in the Netherlands with the purpose of creating a highly medical strain by combining the clear-headed properties of Haze with the overwhelming bounty of resins of Northern Lights and Shiva Skunk.

Jack Herer has been very successful, winning numerous awards, and is highly prescribed by doctors in the Netherlands. It is also becoming increasingly popular among recreational users. This strain has THC levels as high as 23%, which is effective in treating neuropathic pain along with muscle tension, joint pain, back pain, muscle cramps, and pain in the feet and wrists, and more.

This sativa strain helps to ease pain while giving you everything that you would expect from a great sativa. Jack Herer is described as having a pine and earthy like flavor and a CBD range between 0.3% and 2%.


Harlequin Cannabis Strain

Harlequin is a strain that provides a near-perfect combination of cannabinoids that work to relieve nerve pain while ensuring that you never get high. With a typical CBD/THC ratio of 5:2, this is a particularly useful strain for those who suffer from neuropathic pain or epilepsy. It doesn’t come with the same psychoactive effects that are associated with strains with a high THC level, which means that it won’t get you high.

This type of strain is perfect for new cannabis users or those who “fear” the psychoactive high that may accompany strains with a high level of THC. It’s excellent for pain relief because it helps you to relax, soothes nerve pain, and keeps the mind sharp and active.

It’s perfect for morning or daytime use because it gives a light and clear-headed effect that brings forth small urges of focus and energy, and also encourages creativity and a productive work ethic. Along with the potential to treat neuropathic pain, the Harlequin strain has also been used to treat depression, anxiety, and stress.

White Widow

White widow cannabis Strain


The White Widow cannabis strain is one of the most popular in the world. Its main medical use is stress, pain, and insomnia. White Widow originates from the Netherlands and is a half-and-half hybrid between indica and sativa that will make your entire body feel relaxed. For this reason, this strain is best used after work.

In terms of THC percentage, White Widow tops out at a staggering 20% to 25% level, making it one of the strongest and most potent strains in the world. This strain will leave you feeling energized yet relaxed and in a complete state of euphoria, which will allow you to function mentally with maybe just a slightly more positive energy overall. It’s perfect for those who are looking for a strain that will not cause tiredness, lack of energy, or lethargy, yet also won’t feel like complete stimulation in their body. White Widow is the perfect balance between feeling both relaxed and alive.

White Widow is particularly good for those suffering from chronic pain, and more specifically neuropathic pain, since it acts as a neuroprotector and has incredible anti-inflammatory effects on the body.


ADCD Cannabis Strain

ACDC is a sativa-dominant strain that is best known for its pain-killing abilities. What is profound about this strain is that it has a THC:CBD ratio of 1:20, which essentially means that it has no psychoactive effects. Cannabis strains that have a high CBD content won’t alter your mind or cause changes in mood, and also won’t touch the nervous system as other strains do.

A cross between Cannatonic and Ruderalis, ACDC has won several awards thanks to its high CBD content. The smell of this strain is earthy, skunky and sweet, and some may taste a hint of fruit. Due to the balance between sativa and indica, leaning more towards sativa, ACDC usually makes users feel uplifted, experiencing peace, happiness, and euphoria. You may also feel more sociable and focused after using this strain.

The high CBD content of ACDC makes it great for treating inflammatory conditions, and it can help soothe the pain associated with conditions such as fibromyalgia, and, of course, neuropathy. With little to no psychoactive effects, you can expect to experience relaxation while the pain melts away and the mind settles into a peaceful groove.